Irsina holds a significant patrimony of artwork from the 18th century that is attributed to the Campanian artist Andrea Miglionico. His canvasses are found in the Cathedral and the churches of Carmine and Saint Augustine (Sant'Agostino).
In the 18th century, Naples continued to be the point of reference for all art coming from the South of Italy. Paintings from the Neapolitan school, which arrived in Basilicata in this period, drew inspiration from the great master Luca Giordano. One of his best pupils was Andrea Miglionico, who was born in 1663, presumably in the Cilento region around Salerno. His painting style differed to that of Giordano due influences from the Classicism of Venetian painter Paolo Veronese.
Andrea Miglionico's paintings are found in the regions of Campania, Puglia and Basilicata. In Irsina, important works from 1704 to 1706 are held.

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